<span style="font-size:18pt;line-height:100%">Fellow M&M members,</span>
After selling-out our initial stock of 1-T within 24hrs of starting pre-orders on the 1st of November, and being held back by several delays, we have finally shipped out the last of the pre-orders.
Now, we are back on our feet and proud to announce the official 1-T release Ė now instock and ready for immediate shipment directly from Primordial Performance
Also, 1-T logs should be starting very soon. As these are started, I will link them and update this thread.
<span style="font-size:14pt;line-height:100%">Introducing 1-T </span>
1-T is a topical pro-steroid cream delivering high amounts of 1-Androstene-3b-ol, 17-one and 5-Androstene-3b-ol, 17-one. During a 4-6 week cycle, 1-T can produce 10-15lb gains in lean muscle, with minimal side-effects. We believe 1-T is possibly the most effective, yet safest legal pro-steroid product on the market.
<span style="font-size:14pt;line-height:100%"><div align='CENTER'>*** Save 10% with the coupon code SPONSOR10 ***</div></span>
<div align='CENTER'>(Only from Primordial Performance)</div>
For more information, here is the official write upÖ
<blockquote>For this write up, I promised myself Iíd be modest.
The truth is, I am so excited about 1-T that I want to spit out pseudo-science words like super hyperbolic muscle growth, and genetic altering lean mass exploder. And instead of calling it something simple like 1-T, I want to call it AnavarPrimoTestosteroneExtreme.
But I will spare you, simply because this product doesnít need to be hyped. The ingredients and the delivery system tell the story.
So let me jump right inÖ
The first compound is 1-Androstene-3b-ol, 17-one [aka, 1-androsteroneô or 1-DHEA].
This steroid molecule is very closely related to the original 1-androstenediol and 1-testosterone that were very popular prior to the 2004 pro-hormone ban. (1) They produced solid gains in lean muscle within a short period of time, with low side-effects. They where know as ďdryĒ steroid hormones, because they didnít convert to estrogen or promote water retention and gyno. (1)
Unfortunately, those days are long gone. Well, not quiteÖ
Take a look at the hormone conversions below. You will see 1-androsterone is only one step away from 1-androstenediol and two steps away from 1-testosterone. (2)
All it takes is a change on the 3rd or 17th position to convert 1-androsteone into muscle building steroid hormones. These conversions are made with the naturally occurring steroidogenic enzymes -- 3b-HSD and 17b-HSD. (3)
A special advantage of delivering the 1-androsterone topically is the super concentration of steroidogenic enzymes in the skin, compared to a relatively low amount throughout the digestive track. (4-8)
This is exactly what makes 1-T so effective -- 1-androsterone absorbs through the skin, so itís forced to convert to the desired target hormones. (2,4-8)
Having relatively low oral bio-availability and a high price, it was a no-brainer putting 1-androsterone into a topical delivery system. Being that 1-androsterone also has a low molecular weight it can achieve up to 40% delivery through the skin with our OHV topical delivery system, compared to only about 8% orally. (13,14)
1-androsterone as a topical offers the following benefits Ė
<ul>[*]High conversion to 1-androstenediol and 1-testosterone[*]Zero conversion to estrogen[*]Non-methylated and non-toxic to the liver[*]Quality gains in dense lean muscle mass[/list]
Now, this is all very nice, but we wanted to take 1-T to the next level, and create a real muscle builder.
Truthfully, some estrogen is desirable for maximum muscle growth, so we chose a hormone that could fill this void and make 1-T an exceptionally well rounded pro-steroid formula.
In comes 5-Androstene-3b-ol, 17-one. [aka, DHEA]
As you may know, DHEA is the main active ingredient in our other topical product Dermacrine Ė which has proven benefits for improving body composition and strength. As with 1-androsterone, the DHEA is more effective as a topical because it is forced to interact with the steroidogenic enzymes and convert to more powerful anabolic and androgenic hormones that can build muscle and burn fat. (4-12)
Just take a look at the conversions -
Of course, DHEA can also convert to estrogen which supports GH production (11), immunity (15,16), sex drive (17), healthy cholesterol levels (11), and perhaps most importantly Ė rapid gains in muscle mass and size Ė and the engorged feeling of anabolism in the muscles. [known as the pump]
The benefits of DHEA [applied through the skin] could be compared to a moderate dose of injectable testosterone. On the other hand, 1-androsterone could be compared to the anabolic steroid Anavar, Primobolan, or Masteron Ė all of which produce solid gains of ripped, hard, lean muscle.
Common bodybuilder knowledge is that the best gains from testosterone come from stacking it with a non-aromatizing steroid like Anavar, Primobolan or Masteron. This is exactly why we stacked the 1-androsterone with DHEA Ė Itís a match made in steroid guy heaven.
So what does this mean for real-life gains?
If you liked Dermacrine, you will love 1-T. Weíve taken the already proven power of Dermacrine and added the highly anabolic 1-androsterone. 1-T is essentially Dermacrine on steroids.
As the President & Founder of Primordial Performance, I can personally vouch for a solid 14lb gain after a 4 week cycle. I also personally witnessed several local testers break personal bench records and dramatically improve their body composition during 4 and 6 week cycles with 1-T.
The results can be expected to be very similar to the compounds banned in 2004, and hundreds of thousands of bodybuilders and athletes can vouch for these results.
Make no mistake; 1-T is the real deal and is NOT for anyone under the age of 18. Using 1-T will require a proper Post Cycle Therapy (PCT) after a 4-6 week cycle. For more information, please see the Official PCT Thread
If your interested in learning how to best stack and use 1-T based on your goals, see the Official 1-T Cycling & Stacking Thread
Thank you for supporting Primordial Performance.
President & Founder</blockquote>
<blockquote><span style="font-size:8pt;line-height:100%">References -
1. 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties.
A Friedel, et al.
Toxicol Lett, Aug 2006; 165(2): 149-55.
2. Galletti and Gardi, ďMetabolism of 1-Dehydroandrostanes in ManĒ
J Steroid Biochem, 3 (1972), 933-936
3. Chen G, Bourneuf E, Marklund S, Zamaratskaia G, Madej A, LundstrŲm K. Gene expression of 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase in relation to androstenone, testosterone, and estrone sulphate in
gonadally intact male and castrated pigs.
J Anim Sci. 2007 Oct;85(10):2457-63.
4. The metabolism of [4-14C] 5 androstene-3P, 17P-diol by normal human skin in vitro.
Faredin, et al.
Acta Med. Acad. Sci. Hung. 32:139. 1975.
5. Sebocytes are the key regulators of androgen homeostasis in human skin.
M Fritsch, et al.
J Invest Dermatol, May 1, 2001; 116(5): 793-800.
6. The formation of water soluble steroids by human skin.
Berliner, D. L., et al.
J. Invest. Dermatol. 50:220. 1968
7. The metabolism of [4-14C] dehydroepiandrosterone by human skin in vitro. I. Transformation in vitro of [4-14C] dehydroepiandrosterone into Androst-4-ene-3,17-dione, testosterone and androsterone by normal human male and female skin slices.
I Faredin, et al.
Acta Med Acad Sci Hung, Jan 1970; 27(1): 95-102.
8. Activity and inhibition of 3-beta-hydroxysteroid dehydrogenase/delta-5-4-isomerase in human skin.
Skin Pharmacol. 1997;10(3):160-8.
9. Transformation and conjugation of dehydroepiandrosterone by human skin.
Berliner, D. L., et al.
J. Clin. Endocrinol. 27:1214. 1967.
10. The in vitro metabolism of dehydroepiandrosterone in human skin.
I Faredin, et al.
Acta Med Acad Sci Hung, Jan 1967; 23(2): 169-79.
11. Effects of transdermal application of DHEA to men on the levels of steroids, gonadotropins and lipids.
SULCOV√Ā J, et al.
Physiol Res 49: 685-693, 2000.
12. Transformation in vitro of [4-14C ] dehydroepiandrosterone into 7-oxygenated derivatives by the normal human male and female skin tissue.
Faredin, I., et al.
J. Invest. Dermatol. 52:357. 1969
13. Pharmacokinetics of a new testosterone transdermal delivery system, TDS-testosterone in healthy males.
Z Chik, et al.
Br J Clin Pharmacol, Mar 2006; 61(3): 275-9.
14. High bioavailability of dehydroepiandrosterone administered percutaneously in the rat
C Labrie, et al.
Sep 1996; 150: S107 - S118.
15. Androstenediol reduces the anti-inflammatory effects of restraint stress during wound healing.
CC Head, et al.
Brain Behav Immun, Nov 2006; 20(6): 590-6.
16. Androstenetriol improves survival in a rodent model of traumatic shock.
AC Marcu, et al.
Resuscitation, December 1, 2006; 71(3): 379-86.
17. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
Morales AJ, et al.
J Clin Endocrinol Me tab 1994;78:1360- 1367.</span></blockquote>