How exactly does total HPTA "shutdown" occur? What causes the Pituitary to stop all hormone output?
My understanding, though vague, is as follows:
HPTA "shutdown" occurs when too many androgen/estrogen and progesterone receptors become activated in the Hypothalamus. Different AS act in different ways to cause this.
For example, "shutdown" via uses Testosterone is caused by too many estrogen/androgen receptors becoming activated, therefore HPTA "shutdown" occursand the pituitary stops hormone output. Not to mention the negative feedback loop...
Deca and other 19-Nor's will cause HPTA "shutdown" via androgen/progesterone activation as Deca, for example, lacks any estorgenic component.
Is this correct? I must add, the first person to explain this to me was "Ross". Some of you may be aware of him, others not. Is any of the above correct.